ACSF2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ACSF2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,606 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ACSF2-associated genes across cancer lineages are CHAD, FANCI, and TICRR. Each is linked with ACSF2 in more than 7 cancer types. Because this analysis shows association rather than direction, both ACSF2-to-partner and partner-to-ACSF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACSF2 versus CHAD in BRCA, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSF2→partner) and Y-score (partner→ACSF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCACHAD →+1.422+0.468<.001<.00138
COADFANCI →-0.611-0.481<.001<.00136
BRCATICRR →-0.853-0.622<.001<.00136
GBMPRC1 →-0.399-0.440<.001<.00136
LUADABCC6 →+0.903+0.595.002<.00136
COADDNA2 →-0.632-0.529<.001.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,606 associations by consensus.

ACSF2 vs CHAD — BRCA

Per-sample scatter of ACSF2 vs CHAD in BRCA (Pearson r = 0.39).

Explore this scatter interactively →

Exploration