ACSF2

Across TCGA cell cohorts, ACSF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,931 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ACSF2-associated GO terms across cancer lineages are Negative regulation of protein-containing complex assembly, Viral process, and Small GTPase-mediated signal transduction. Each is linked with ACSF2 in more than 12 cancer types. Because this analysis shows association rather than direction, both ACSF2-to-partner and partner-to-ACSF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein-containing complex assembly grouped by ACSF2-low versus ACSF2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSF2→partner) and Y-score (partner→ACSF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Negative regulation of protein-containing complex assembly →	+0.096	+2.244	<.001	<.001	3	13
STOMACH	Viral process →	+0.107	+1.950	<.001	.001	3	13
UPPER_AERODIGESTIVE_TRACT	Small GTPase-mediated signal transduction →	+0.059	+1.570	.002	<.001	3	13
URINARY_TRACT	Negative regulation of transforming growth factor beta production →	+0.321	+2.600	<.001	.001	3	12
BONE	Rho protein signal transduction →	+0.133	+2.143	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.114	+1.057	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,931 associations by consensus.

Negative regulation of protein-containing complex assembly by ACSF2 expression — URINARY_TRACT

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