ACSF2

Across TCGA cell cohorts, ACSF2 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACSF2-associated genes across cancer lineages are CD300LD, RD3L, and SPO11. Each is linked with ACSF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACSF2-to-partner and partner-to-ACSF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD300LD grouped by ACSF2-low versus ACSF2-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSF2→partner) and Y-score (partner→ACSF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	CD300LD →	+0.022	+5.029	<.001	.006	3	1
LUNG_SCLC	RD3L →	+0.032	+5.029	<.001	.006	3	1
LUNG_SCLC	SPO11 →	+0.066	+5.029	<.001	.006	3	1
BLOOD_Leukemia	WNT3A →	+0.042	+3.474	<.001	.007	3	1
BLOOD_Leukemia	ADGRF2 →	+0.024	+3.359	<.001	.002	3	1
BLOOD_Leukemia	CTRB2 →	+0.059	+3.177	.007	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

CD300LD by ACSF2 expression — LUNG_SCLC

Explore this box plot interactively →