ACSBG2

Across TCGA patient cohorts, ACSBG2 mutation is significantly associated with the RNA expression of many other genes, with 4,092 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACSBG2-associated genes across cancer lineages are U2AF2, TRAPPC2P8, and RNA5SP412. Each is linked with ACSBG2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ACSBG2-to-partner and partner-to-ACSBG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, U2AF2 grouped by ACSBG2-low versus ACSBG2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSBG2→partner) and Y-score (partner→ACSBG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	U2AF2 →	+0.355	+2.791	<.001	<.001	3	3
CESC	TRAPPC2P8 →	+0.058	+6.589	<.001	<.001	3	3
UCEC	RNA5SP412 →	+0.550	+1.726	<.001	.001	3	3
BRCA	RN7SL62P →	+0.098	+4.971	<.001	.005	3	3
LUAD	RNU6-912P →	+0.442	+4.628	.002	.004	3	3
LUAD	APOOP2 →	+0.707	+5.575	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,092 associations by consensus.

U2AF2 by ACSBG2 expression — UCEC

Explore this box plot interactively →