ACSBG2

Across TCGA cell cohorts, ACSBG2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ACSBG2-associated genes across cancer lineages are FHL5, GAGE12J, and RNASE8. Each is linked with ACSBG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACSBG2-to-partner and partner-to-ACSBG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FHL5 grouped by ACSBG2-low versus ACSBG2-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSBG2→partner) and Y-score (partner→ACSBG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	FHL5 →	+0.023	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	GAGE12J →	+0.266	+4.643	<.001	.008	3	1
LARGE_INTESTINE	RNASE8 →	+0.051	+3.930	<.001	.003	3	1
LARGE_INTESTINE	HNRNPCL4 →	+0.049	+3.793	.004	.007	3	1
LARGE_INTESTINE	ADH1A →	+0.216	+3.920	<.001	.005	3	1
OVARY	CDRT15L2 →	+0.022	+5.196	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

FHL5 by ACSBG2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →