ACSBG1

Across TCGA patient cohorts, ACSBG1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,037 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ACSBG1-associated genes across cancer lineages are PLEK2, INVS, and CYTH4. Each is linked with ACSBG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACSBG1-to-partner and partner-to-ACSBG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACSBG1 versus PLEK2 in BRCA, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSBG1→partner) and Y-score (partner→ACSBG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PLEK2 →	+1.228	+0.684	.002	.005	3	1
BRCA	INVS →	-0.472	-0.648	.002	.009	3	1
GBM	CYTH4 →	-0.643	-0.449	<.001	<.001	3	1
GBM	SH3BP1 →	-0.318	-0.367	.004	.008	3	1
GBM	GCAT →	+0.586	+0.635	.001	<.001	3	1
GBM	XBP1 →	-0.395	-0.379	.005	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,037 associations by consensus.

ACSBG1 vs PLEK2 — BRCA

Explore this scatter interactively →