ACSBG1

Across TCGA pan-cancer cohorts, ACSBG1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of ACSBG1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where ACSBG1 RNA is repressed in tumor relative to normal tissue. In most cancer types ACSBG1 is over-expressed in tumor, although a few such as LUAD and COAD show the opposite, repressed pattern.

LUAD, COAD, and KICH are the cancer types where ACSBG1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ACSBG1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	II,III,IV	−0.415	<.001	8	view →
COAD	Male	II,III,IV	−0.175	<.001	7	view →
KICH	All	All	+0.523	.001	6	view →
LUSC	All	II,III,IV	−0.428	<.001	6	view →
CHOL	All	All	+0.103	.005	3	view →
STAD	All	All	−0.180	.014	1	view →
THCA	Female	II,III,IV	−0.042	.049	1	view →
LIHC	Female	All	+0.033	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

ACSBG1–LUAD

Open the LUAD breakdown →