ACSBG1

Across TCGA patient cohorts, ACSBG1 mutation is significantly associated with the RNA expression of many other genes, with 4,682 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACSBG1-associated genes across cancer lineages are MTND2P6, PSMA3, and ZPR1. Each is linked with ACSBG1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ACSBG1-to-partner and partner-to-ACSBG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND2P6 grouped by ACSBG1-low versus ACSBG1-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSBG1→partner) and Y-score (partner→ACSBG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MTND2P6 →	+0.040	+4.241	.001	.002	3	3
UCEC	PSMA3 →	+0.410	+1.968	<.001	<.001	2	4
UCEC	ZPR1 →	+0.345	+2.243	.001	<.001	3	3
UCEC	MASTL →	+0.501	+2.222	.001	<.001	3	3
UCEC	AUNIP →	+0.715	+2.536	<.001	<.001	3	3
UCEC	PPIL4 →	+0.528	+2.233	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,682 associations by consensus.

MTND2P6 by ACSBG1 expression — HNSC

Explore this box plot interactively →