ACSBG1

Across TCGA cell cohorts, ACSBG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,144 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACSBG1-associated GO terms across cancer lineages are Negative regulation of mRNA processing, Negative regulation of RNA splicing, and Cellular respiration. Each is linked with ACSBG1 in more than 9 cancer types. Because this analysis shows association rather than direction, both ACSBG1-to-partner and partner-to-ACSBG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mRNA processing grouped by ACSBG1-low versus ACSBG1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSBG1→partner) and Y-score (partner→ACSBG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of mRNA processing →	+0.094	+0.338	<.001	.008	3	10
BLOOD_Lymphoma	Negative regulation of RNA splicing →	+0.094	+0.349	<.001	.002	3	9
UPPER_AERODIGESTIVE_TRACT	Cellular respiration →	+0.073	+0.198	.001	.006	3	9
PANCREAS	Regulation of mRNA processing →	+0.075	+0.316	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Aerobic respiration →	+0.079	+0.257	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Mitotic DNA integrity checkpoint signaling →	+0.062	+0.201	.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,144 associations by consensus.

Negative regulation of mRNA processing by ACSBG1 expression — LARGE_INTESTINE

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