ACSBG1

Across TCGA cell cohorts, ACSBG1 mutation is significantly associated with the RNA expression of many other genes, with 594 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ACSBG1-associated genes across cancer lineages are AMELY, PRSS58, and TNP2. Each is linked with ACSBG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACSBG1-to-partner and partner-to-ACSBG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AMELY grouped by ACSBG1-low versus ACSBG1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSBG1→partner) and Y-score (partner→ACSBG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	AMELY →	+0.027	+4.415	<.001	.007	3	2
PANCREAS	PRSS58 →	+0.092	+5.000	<.001	.006	3	1
OESOPHAGUS	TNP2 →	+0.023	+4.392	<.001	.003	3	1
OESOPHAGUS	TSPY10 →	+0.050	+4.017	<.001	.007	3	1
LUNG_NSCLC_LUAD	GABRA6 →	+0.096	+5.189	<.001	<.001	3	1
LUNG_NSCLC_LUAD	TAAR8 →	+0.017	+4.662	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 594 associations by consensus.

AMELY by ACSBG1 expression — SKIN

Explore this box plot interactively →