ACRV1

Across TCGA patient cohorts, ACRV1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,733 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ACRV1-associated proteins across cancer lineages are MKI67_S1679, NDC80, and TOP2A. Each is linked with ACRV1 in more than 7 cancer types. Because this analysis shows association rather than direction, both ACRV1-to-partner and partner-to-ACRV1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACRV1 versus MKI67_S1679 in BRCA, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ACRV1→partner) and Y-score (partner→ACRV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MKI67_S1679 →	+1.159	+0.375	<.001	<.001	3	8
LUAD	NDC80 →	+0.728	+0.527	<.001	<.001	3	8
LUAD	TOP2A →	+1.067	+0.525	<.001	<.001	3	8
LUAD	TPX2 →	+0.881	+0.550	<.001	<.001	3	8
BRCA	UBE2T →	+0.745	+0.266	<.001	<.001	3	8
HNSC	RFC2 →	+0.341	+0.614	.003	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,733 associations by consensus.

ACRV1 vs MKI67_S1679 — BRCA

Explore this scatter interactively →