ACRBP

Across TCGA patient cohorts, ACRBP protein abundance is significantly associated with the RNA expression of many other genes, with 11,161 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ACRBP-associated genes across cancer lineages are PTK7, LOXL1, and PLAAT2. Each is linked with ACRBP in more than 1 cancer types. Because this analysis shows association rather than direction, both ACRBP-to-partner and partner-to-ACRBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACRBP versus PTK7 in GBM, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACRBP→partner) and Y-score (partner→ACRBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PTK7 →	+1.063	+0.873	.009	.005	3	1
GBM	LOXL1 →	+1.883	+0.873	.001	.005	3	1
GBM	PLAAT2 →	+0.631	+1.028	.004	<.001	3	1
GBM	B4GALNT3 →	+1.616	+0.873	.006	.005	3	1
GBM	ZDHHC5 →	+0.548	+0.941	.002	.006	3	1
GBM	ASGR2 →	+1.010	+1.028	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,161 associations by consensus.

ACRBP vs PTK7 — GBM

Explore this scatter interactively →