ACP4

Across TCGA cell cohorts, ACP4 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ACP4-associated genes across cancer lineages are PGK2, KRTAP17-1, and KRT33A. Each is linked with ACP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACP4-to-partner and partner-to-ACP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PGK2 grouped by ACP4-low versus ACP4-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACP4→partner) and Y-score (partner→ACP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	PGK2 →	+0.209	+4.930	<.001	.008	3	1
SOFT_TISSUE	KRTAP17-1 →	+0.016	+5.369	<.001	.004	3	1
SOFT_TISSUE	KRT33A →	+0.058	+4.930	<.001	.008	3	1
SKIN	SCGB2A1 →	+0.069	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

PGK2 by ACP4 expression — SOFT_TISSUE

Explore this box plot interactively →