ACP3

Across TCGA cell cohorts, ACP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,587 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACP3-associated GO terms across cancer lineages are Positive regulation of cell communication by electrical coupling, Negative regulation of delayed rectifier potassium channel activity, and Adenosine metabolic process. Each is linked with ACP3 in more than 11 cancer types. Because this analysis shows association rather than direction, both ACP3-to-partner and partner-to-ACP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell communication by electrical coupling grouped by ACP3-low versus ACP3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACP3→partner) and Y-score (partner→ACP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of cell communication by electrical coupling →	+1.599	+1.168	.001	.002	2	12
BONE	Negative regulation of delayed rectifier potassium channel activity →	+1.704	+1.786	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Adenosine metabolic process →	-0.264	-0.927	.001	<.001	3	11
LARGE_INTESTINE	T cell mediated cytotoxicity →	+0.168	+1.339	<.001	<.001	3	10
URINARY_TRACT	Phospholipid biosynthetic process →	+0.048	+1.816	<.001	<.001	3	9
PANCREAS	Intracellular sodium ion homeostasis →	+0.225	+0.640	.002	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,587 associations by consensus.

Positive regulation of cell communication by electrical coupling by ACP3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →