ACP2

Across TCGA patient cohorts, ACP2 mutation is significantly associated with the RNA expression of many other genes, with 903 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACP2-associated genes across cancer lineages are RNU6-982P, CYP4F36P, and REXO1L8P. Each is linked with ACP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ACP2-to-partner and partner-to-ACP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-982P grouped by ACP2-low versus ACP2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACP2→partner) and Y-score (partner→ACP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-982P →	+0.488	+7.731	<.001	.009	3	3
UCEC	CYP4F36P →	+0.234	+2.105	.006	.006	3	2
SKCM	REXO1L8P →	+0.009	+4.147	<.001	.008	3	2
CESC	FAM8A2P →	+0.043	+5.539	<.001	.004	3	2
COAD	RN7SL478P →	+0.458	+4.145	<.001	.002	3	2
UCEC	TDGF1P1 →	+0.072	+3.042	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 903 associations by consensus.

RNU6-982P by ACP2 expression — BRCA

Explore this box plot interactively →