ACOXL

Across TCGA patient cohorts, ACOXL RNA expression is significantly associated with the protein abundance of many other proteins, with 17,086 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ACOXL-associated proteins across cancer lineages are TPI1_S80, MMP14, and PLOD1. Each is linked with ACOXL in more than 3 cancer types. Because this analysis shows association rather than direction, both ACOXL-to-partner and partner-to-ACOXL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACOXL versus TPI1_S80 in LSCC, with a Pearson correlation of -0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ACOXL→partner) and Y-score (partner→ACOXL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TPI1_S80 →	-0.573	-0.740	<.001	<.001	3	4
GBM	MMP14 →	-0.697	-0.228	<.001	<.001	3	4
GBM	PLOD1 →	-0.563	-0.132	<.001	.001	3	4
HNSC	PPP1R9A_S840 →	+1.483	+0.537	<.001	<.001	3	4
LSCC	CARMIL2_S1381 →	+0.731	+0.595	<.001	<.001	3	4
HNSC	AHNAK2 →	-0.802	-0.707	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,086 associations by consensus.

ACOXL vs TPI1_S80 — LSCC

Explore this scatter interactively →