ACOXL

Across TCGA cell cohorts, ACOXL RNA expression is significantly associated with the go_rna of many other GO terms, with 3,511 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ACOXL-associated GO terms across cancer lineages are Cellular response to indole-3-methanol, Regulation of intracellular protein transport, and Positive regulation of intracellular transport. Each is linked with ACOXL in more than 8 cancer types. Because this analysis shows association rather than direction, both ACOXL-to-partner and partner-to-ACOXL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to indole-3-methanol grouped by ACOXL-low versus ACOXL-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACOXL→partner) and Y-score (partner→ACOXL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Cellular response to indole-3-methanol →	+0.165	+2.275	<.001	<.001	3	9
OESOPHAGUS	Regulation of intracellular protein transport →	+0.062	+1.051	<.001	.003	3	8
LARGE_INTESTINE	Positive regulation of intracellular transport →	+0.043	+0.623	<.001	<.001	3	8
URINARY_TRACT	Response to indole-3-methanol →	+0.193	+1.722	<.001	<.001	3	8
LUNG_NSCLC_LUAD	Positive regulation of lung ciliated cell differentiation →	+0.842	+1.070	<.001	<.001	3	8
LUNG_NSCLC_LUAD	Regulation of high-density lipoprotein particle clearance →	+0.974	+1.209	.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,511 associations by consensus.

Cellular response to indole-3-methanol by ACOXL expression — URINARY_TRACT

Explore this box plot interactively →