ACOT8

Across TCGA cell cohorts, ACOT8 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,947 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ACOT8-associated GO terms across cancer lineages are Insulin receptor recycling, Positive regulation by virus of viral protein levels in host cell, and Protein-containing complex disassembly. Each is linked with ACOT8 in more than 11 cancer types. Because this analysis shows association rather than direction, both ACOT8-to-partner and partner-to-ACOT8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Insulin receptor recycling grouped by ACOT8-low versus ACOT8-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACOT8→partner) and Y-score (partner→ACOT8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Insulin receptor recycling →	+0.165	+0.657	<.001	<.001	3	12
KIDNEY	Positive regulation by virus of viral protein levels in host cell →	+0.129	+0.727	.001	.007	3	11
SOFT_TISSUE	Protein-containing complex disassembly →	+0.067	+0.795	<.001	<.001	3	11
STOMACH	Golgi to plasma membrane protein transport →	+0.122	+0.954	.008	<.001	3	10
OVARY	Alpha-linolenic acid metabolic process →	+0.174	+1.051	<.001	<.001	3	10
URINARY_TRACT	Endosomal transport →	+0.043	+0.626	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,947 associations by consensus.

Insulin receptor recycling by ACOT8 expression — BONE

Explore this box plot interactively →