ACOT7

Across TCGA patient cohorts, ACOT7 mutation is significantly associated with the RNA expression of many other genes, with 2,441 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACOT7-associated genes across cancer lineages are FXYD6P3, RNU6-1231P, and RNU4-30P. Each is linked with ACOT7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACOT7-to-partner and partner-to-ACOT7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FXYD6P3 grouped by ACOT7-low versus ACOT7-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACOT7→partner) and Y-score (partner→ACOT7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	FXYD6P3 →	+0.145	+4.899	<.001	.005	3	2
BLCA	RNU6-1231P →	+0.538	+4.208	<.001	.009	3	2
SKCM	RNU4-30P →	+0.326	+5.771	<.001	.003	3	2
SKCM	LINC01153 →	+0.028	+5.513	<.001	.004	3	2
UCEC	CLN8 →	+0.658	+3.732	<.001	<.001	3	2
UCEC	CDCA2 →	+1.093	+3.087	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,441 associations by consensus.

FXYD6P3 by ACOT7 expression — BLCA

Explore this box plot interactively →