ACOT7

Across TCGA cell cohorts, ACOT7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,479 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACOT7-associated GO terms across cancer lineages are Mitotic spindle midzone assembly, Chromosome segregation, and Mitotic spindle elongation. Each is linked with ACOT7 in more than 14 cancer types. Because this analysis shows association rather than direction, both ACOT7-to-partner and partner-to-ACOT7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic spindle midzone assembly grouped by ACOT7-low versus ACOT7-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACOT7→partner) and Y-score (partner→ACOT7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Mitotic spindle midzone assembly →	+0.289	+1.277	.003	<.001	3	15
BLOOD_Myeloma	Chromosome segregation →	+0.090	+2.051	.001	<.001	3	15
OESOPHAGUS	Mitotic spindle elongation →	+0.289	+1.277	.003	<.001	3	15
OESOPHAGUS	Regulation of cell cycle checkpoint →	+0.157	+0.893	<.001	.004	3	14
KIDNEY	Regulation of mitotic metaphase/anaphase transition →	+0.121	+1.576	<.001	<.001	3	14
BLOOD_Myeloma	Nuclear chromosome segregation →	+0.101	+1.693	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,479 associations by consensus.

Mitotic spindle midzone assembly by ACOT7 expression — OESOPHAGUS

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