ACMSD

Across TCGA cell cohorts, ACMSD mutation is significantly associated with the mutation status of many other genes, with 1,722 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ACMSD-associated genes across cancer lineages are TATDN2, MYORG, and HOXC10. Each is linked with ACMSD in more than 1 cancer types. Because this analysis shows association rather than direction, both ACMSD-to-partner and partner-to-ACMSD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TATDN2 grouped by ACMSD-low versus ACMSD-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACMSD→partner) and Y-score (partner→ACMSD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	TATDN2 →	+5.502	+5.502	.003	.003	1	2
LUNG_SCLC	MYORG →	+4.502	+5.066	.007	.007	1	2
LUNG_SCLC	HOXC10 →	+5.502	+5.502	.003	.003	1	2
LUNG_SCLC	PLCXD2 →	+5.502	+5.502	.003	.003	1	2
LUNG_SCLC	NBPF10 →	+4.502	+5.066	.007	.007	1	2
LARGE_INTESTINE	POLRMT →	+1.836	+2.906	.009	.009	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,722 associations by consensus.

TATDN2 by ACMSD expression — LUNG_SCLC

Explore this box plot interactively →