ACIN1

Across TCGA patient cohorts, ACIN1 mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACIN1-associated genes across cancer lineages are GATA3, FoxM1, and GAPDH. Each is linked with ACIN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ACIN1-to-partner and partner-to-ACIN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GATA3 grouped by ACIN1-low versus ACIN1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACIN1→partner) and Y-score (partner→ACIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	GATA3 →	+0.785	+3.169	.001	.017	3	3
UCEC	FoxM1 →	+0.190	+2.432	.020	<.001	3	3
UCEC	GAPDH →	+0.389	+1.584	.021	.034	3	3
UCEC	RAD51 →	+0.106	+1.678	.016	.021	3	3
UCEC	Caspase-7-cleavedD198 →	+0.623	+2.415	<.001	.002	3	3
STAD	ERK2 →	+0.326	+3.000	.041	.036	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

GATA3 by ACIN1 expression — BLCA

Explore this box plot interactively →