ACIN1

Across TCGA cell cohorts, ACIN1 mutation is significantly associated with the RNA expression of many other genes, with 460 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ACIN1-associated genes across cancer lineages are KRT33A, ETDB, and KCNK17. Each is linked with ACIN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ACIN1-to-partner and partner-to-ACIN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRT33A grouped by ACIN1-low versus ACIN1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACIN1→partner) and Y-score (partner→ACIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	KRT33A →	+0.037	+4.930	<.001	.008	3	3
BLOOD_Leukemia	ETDB →	+0.031	+2.644	.004	.008	3	3
LARGE_INTESTINE	KCNK17 →	+0.040	+2.366	.008	.007	3	2
LARGE_INTESTINE	SMIM33 →	+0.578	+3.770	<.001	<.001	3	2
BLOOD_Leukemia	LY6H →	+0.807	+2.855	.006	.002	3	2
BLOOD_Leukemia	TMEM213 →	+0.048	+2.491	.004	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 460 associations by consensus.

KRT33A by ACIN1 expression — SOFT_TISSUE

Explore this box plot interactively →