ACER3

Across TCGA cell cohorts, ACER3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,735 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ACER3-associated GO terms across cancer lineages are Phosphatidylinositol biosynthetic process, Microtubule organizing center organization, and Centrosome cycle. Each is linked with ACER3 in more than 11 cancer types. Because this analysis shows association rather than direction, both ACER3-to-partner and partner-to-ACER3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphatidylinositol biosynthetic process grouped by ACER3-low versus ACER3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACER3→partner) and Y-score (partner→ACER3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol biosynthetic process →	+0.068	+1.457	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Microtubule organizing center organization →	+0.075	+1.201	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Centrosome cycle →	+0.085	+1.085	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol metabolic process →	+0.051	+1.259	<.001	<.001	3	10
SOFT_TISSUE	Schwann cell differentiation →	+0.120	+0.587	<.001	.007	3	10
SOFT_TISSUE	Schwann cell development →	+0.118	+0.677	.001	.006	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,735 associations by consensus.

Phosphatidylinositol biosynthetic process by ACER3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →