ACBD5

Across TCGA patient cohorts, ACBD5 mutation is significantly associated with the RNA expression of many other genes, with 1,064 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACBD5-associated genes across cancer lineages are RNA5SP146, DNAJB6P4, and RNA5SP156. Each is linked with ACBD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACBD5-to-partner and partner-to-ACBD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP146 grouped by ACBD5-low versus ACBD5-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACBD5→partner) and Y-score (partner→ACBD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RNA5SP146 →	+0.366	+5.653	<.001	.003	3	2
LUAD	DNAJB6P4 →	+0.068	+3.127	.005	.007	3	2
SKCM	RNA5SP156 →	+0.231	+4.797	<.001	.003	3	2
SKCM	LINC02679 →	+0.241	+3.911	<.001	.004	3	2
BLCA	RPL22P21 →	+0.203	+4.057	<.001	.001	3	2
BLCA	RN7SL310P →	+0.218	+3.681	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,064 associations by consensus.

RNA5SP146 by ACBD5 expression — READ

Explore this box plot interactively →