ACAT1

Across TCGA cell cohorts, ACAT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,487 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible ACAT1-associated GO terms across cancer lineages are Acetyl-CoA catabolic process, Platelet activating factor catabolic process, and Ether catabolic process. Each is linked with ACAT1 in more than 18 cancer types. Because this analysis shows association rather than direction, both ACAT1-to-partner and partner-to-ACAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Acetyl-CoA catabolic process grouped by ACAT1-low versus ACAT1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACAT1→partner) and Y-score (partner→ACAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Acetyl-CoA catabolic process →	+0.197	+1.363	<.001	.001	3	19
OESOPHAGUS	Platelet activating factor catabolic process →	+0.192	+1.528	.004	.002	2	17
OESOPHAGUS	Ether catabolic process →	+0.192	+1.528	.004	.002	2	17
OESOPHAGUS	Glycerol ether catabolic process →	+0.192	+1.528	.004	.002	2	17
UPPER_AERODIGESTIVE_TRACT	Asparaginyl-tRNA aminoacylation →	+0.153	+1.460	.004	<.001	3	14
URINARY_TRACT	IMP biosynthetic process →	+0.176	+1.153	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,487 associations by consensus.

Acetyl-CoA catabolic process by ACAT1 expression — OESOPHAGUS

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