Across TCGA cell cohorts, ACADSB mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ACADSB-associated genes across cancer lineages are ACER1, OR2C1, and WDR87. Each is linked with ACADSB in more than 1 cancer types. Because this analysis shows association rather than direction, both ACADSB-to-partner and partner-to-ACADSB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACADSB→partner) and Y-score (partner→ACADSB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ACER1 →	+0.072	+4.145	.006	.001	3	1
LARGE_INTESTINE	OR2C1 →	+0.090	+3.578	.004	.006	3	1
LARGE_INTESTINE	WDR87 →	+0.019	+4.353	<.001	.001	3	1
LARGE_INTESTINE	OR10W1 →	+0.010	+3.562	<.001	.002	3	1
LARGE_INTESTINE	ACSM6 →	+0.024	+3.584	<.001	.002	3	1
LARGE_INTESTINE	IQCF6 →	+0.208	+3.297	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

ACADSB survival (RNA) · tumor vs normal (RNA) · all ACADSB data types