ACADS

Across TCGA patient cohorts, ACADS mutation is significantly associated with the RNA expression of many other genes, with 1,387 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACADS-associated genes across cancer lineages are MIR3188, MIR6515, and TRAJ52. Each is linked with ACADS in more than 1 cancer types. Because this analysis shows association rather than direction, both ACADS-to-partner and partner-to-ACADS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3188 grouped by ACADS-low versus ACADS-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACADS→partner) and Y-score (partner→ACADS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR3188 →	+0.767	+3.333	<.001	.001	3	2
SKCM	MIR6515 →	+0.275	+5.163	<.001	.002	3	2
HNSC	TRAJ52 →	+0.637	+5.241	<.001	.007	3	2
HNSC	MIR3121 →	+0.610	+6.468	<.001	.001	3	2
UCEC	NCR1 →	+0.253	+2.624	.007	.005	3	2
UCEC	RNU6-728P →	+0.170	+3.335	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,387 associations by consensus.

MIR3188 by ACADS expression — COAD

Explore this box plot interactively →