ACADM

Across TCGA patient cohorts, ACADM mutation is significantly associated with the RNA expression of many other genes, with 1,233 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACADM-associated genes across cancer lineages are RNU4-65P, MRPS15P1, and TCF4-AS1. Each is linked with ACADM in more than 1 cancer types. Because this analysis shows association rather than direction, both ACADM-to-partner and partner-to-ACADM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-65P grouped by ACADM-low versus ACADM-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACADM→partner) and Y-score (partner→ACADM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RNU4-65P →	+0.275	+4.672	<.001	.004	3	2
READ	MRPS15P1 →	+0.072	+3.827	.005	.006	3	2
READ	TCF4-AS1 →	+0.113	+4.672	<.001	.004	3	2
LIHC	RNU6-1022P →	+0.397	+6.902	<.001	<.001	3	2
LUAD	RNA5SP110 →	+0.182	+4.303	.002	.009	3	2
LUAD	PSAT1P4 →	+0.136	+4.157	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,233 associations by consensus.

RNU4-65P by ACADM expression — READ

Explore this box plot interactively →