ACADM

Across TCGA cell cohorts, ACADM mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ACADM-associated genes across cancer lineages are HOXB1, TAS2R7, and IAPP. Each is linked with ACADM in more than 1 cancer types. Because this analysis shows association rather than direction, both ACADM-to-partner and partner-to-ACADM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HOXB1 grouped by ACADM-low versus ACADM-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACADM→partner) and Y-score (partner→ACADM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	HOXB1 →	+0.019	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	TAS2R7 →	+0.032	+5.643	<.001	.002	3	1
LARGE_INTESTINE	IAPP →	+0.469	+4.228	<.001	.001	3	1
LARGE_INTESTINE	FCGR3B →	+0.097	+3.297	.005	.002	3	1
LARGE_INTESTINE	BPIFB6 →	+0.014	+3.700	<.001	.009	3	1
LARGE_INTESTINE	ODF3 →	+0.050	+3.836	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

HOXB1 by ACADM expression — BLOOD_Lymphoma

Explore this box plot interactively →