ACAD9

Across TCGA patient cohorts, ACAD9 mutation is significantly associated with the RNA expression of many other genes, with 2,497 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACAD9-associated genes across cancer lineages are MTND6P32, NOCT, and NCAPD3. Each is linked with ACAD9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACAD9-to-partner and partner-to-ACAD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND6P32 grouped by ACAD9-low versus ACAD9-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACAD9→partner) and Y-score (partner→ACAD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	MTND6P32 →	+0.188	+6.257	<.001	.001	3	2
UCEC	NOCT →	+0.617	+2.069	<.001	<.001	3	2
UCEC	NCAPD3 →	+0.537	+1.522	<.001	.009	3	2
UCEC	PANK4 →	+0.367	+1.952	<.001	.004	3	2
UCEC	SLC30A2 →	-0.863	-1.999	.002	.002	3	2
UCEC	ADAMTS4 →	+0.433	+3.711	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,497 associations by consensus.

MTND6P32 by ACAD9 expression — READ

Explore this box plot interactively →