ACAD9

Across TCGA pan-cancer cohorts, ACAD9 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of ACAD9’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ACAD9 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ACAD9 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

COAD, BLCA, and LIHC are the cancer types where ACAD9 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ACAD9 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	+0.716	<.001	11	view →
BLCA	All	III,IV	+0.496	<.001	10	view →
LIHC	Female	II,III,IV	+0.830	<.001	9	view →
LUSC	Male	II,III,IV	+0.778	<.001	8	view →
HNSC	Male	IV	+0.690	<.001	8	view →
CHOL	Female	All	+1.360	<.001	5	view →
KIRC	Female	All	+0.428	<.001	5	view →
KICH	All	All	−0.494	.001	4	view →
STAD	All	II,III,IV	+0.430	.014	3	view →
THCA	Male	III,IV	−0.274	.002	3	view →
PAAD	Female	All	+0.149	.027	2	view →
ESCA	All	All	+0.587	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

ACAD9–COAD

Open the COAD breakdown →