ACAA2

Across TCGA cell cohorts, ACAA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,161 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ACAA2-associated GO terms across cancer lineages are Negative regulation of mitochondrial membrane permeability involved in apoptotic process, Positive regulation of hemostasis, and Positive regulation of blood coagulation. Each is linked with ACAA2 in more than 10 cancer types. Because this analysis shows association rather than direction, both ACAA2-to-partner and partner-to-ACAA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mitochondrial membrane permeability involved in apoptotic process grouped by ACAA2-low versus ACAA2-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACAA2→partner) and Y-score (partner→ACAA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Negative regulation of mitochondrial membrane permeability involved in apoptotic process →	+0.360	+2.203	<.001	.009	3	11
LUNG_SCLC	Positive regulation of hemostasis →	-0.145	-0.669	<.001	<.001	3	7
LUNG_SCLC	Positive regulation of blood coagulation →	-0.145	-0.669	<.001	<.001	3	7
LUNG_SCLC	Positive regulation of coagulation →	-0.186	-0.719	<.001	<.001	3	7
LUNG_SCLC	Asparaginyl-tRNA aminoacylation →	+0.137	+0.583	.004	.009	2	8
LUNG_NSCLC_LUSC	Regulation of mitochondrial membrane permeability involved in apoptotic process →	+0.122	+2.222	.003	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,161 associations by consensus.

Negative regulation of mitochondrial membrane permeability involved in apoptotic process by ACAA2 expression — KIDNEY

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