ABRA

Across TCGA cell cohorts, ABRA RNA expression is significantly associated with the go_rna of many other GO terms, with 712 significant associations in total. KIDNEY shows the largest number of these associations.

The most reproducible ABRA-associated GO terms across cancer lineages are Resolution of mitotic recombination intermediates, Cellular response to hydroperoxide, and Negative regulation of mRNA metabolic process. Each is linked with ABRA in more than 4 cancer types. Because this analysis shows association rather than direction, both ABRA-to-partner and partner-to-ABRA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Resolution of mitotic recombination intermediates grouped by ABRA-low versus ABRA-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABRA→partner) and Y-score (partner→ABRA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Resolution of mitotic recombination intermediates →	+0.122	+0.050	.003	<.001	3	5
OESOPHAGUS	Cellular response to hydroperoxide →	+0.161	+0.023	.006	.007	3	5
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mRNA metabolic process →	+0.055	+0.031	.001	.009	3	4
UPPER_AERODIGESTIVE_TRACT	Negative regulation of insulin-like growth factor receptor signaling pathway →	+0.151	+0.027	.001	<.001	3	4
STOMACH	Fc-epsilon receptor signaling pathway →	+0.064	+0.032	<.001	.008	3	4
PANCREAS	Sperm motility →	-0.053	-0.030	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 712 associations by consensus.

Resolution of mitotic recombination intermediates by ABRA expression — LUNG_SCLC

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