ABLIM3

Across TCGA patient cohorts, ABLIM3 mutation is significantly associated with the RNA expression of many other genes, with 3,401 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABLIM3-associated genes across cancer lineages are PSMC5, RNU6-764P, and JMJD6. Each is linked with ABLIM3 in more than 3 cancer types. Because this analysis shows association rather than direction, both ABLIM3-to-partner and partner-to-ABLIM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSMC5 grouped by ABLIM3-low versus ABLIM3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABLIM3→partner) and Y-score (partner→ABLIM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PSMC5 →	+0.396	+2.542	.004	.009	3	4
LUAD	RNU6-764P →	+0.135	+4.526	<.001	.004	3	3
UCEC	JMJD6 →	+0.493	+1.632	<.001	<.001	3	3
READ	LINC00326 →	+0.635	+4.421	<.001	.009	3	2
UCEC	POM121C →	+0.312	+1.761	<.001	.004	3	2
UCEC	CYFIP1 →	+0.322	+1.547	.009	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,401 associations by consensus.

PSMC5 by ABLIM3 expression — SKCM

Explore this box plot interactively →