ABLIM3

Across TCGA cell cohorts, ABLIM3 mutation is significantly associated with the RNA expression of many other genes, with 72 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABLIM3-associated genes across cancer lineages are MROH5, CA5A, and DEFA3. Each is linked with ABLIM3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABLIM3-to-partner and partner-to-ABLIM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MROH5 grouped by ABLIM3-low versus ABLIM3-high in BONE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABLIM3→partner) and Y-score (partner→ABLIM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	MROH5 →	+0.006	+5.169	<.001	.004	3	2
LUNG_NSCLC_LUAD	CA5A →	+0.056	+3.243	.005	.001	3	2
CNS	DEFA3 →	+0.040	+4.772	<.001	.002	3	2
BONE	OBP2B →	+0.123	+5.169	<.001	.004	3	1
SOFT_TISSUE	OR4K1 →	+0.010	+3.977	<.001	.007	3	1
SOFT_TISSUE	OR56B1 →	+0.008	+3.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 72 associations by consensus.

MROH5 by ABLIM3 expression — BONE

Explore this box plot interactively →