ABLIM2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ABLIM2 mutation is significantly associated with the RNA expression of many other genes, with 3,819 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABLIM2-associated genes across cancer lineages are TDGF1P1, PSMC3IP, and RN7SL248P. Each is linked with ABLIM2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ABLIM2-to-partner and partner-to-ABLIM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TDGF1P1 grouped by ABLIM2-low versus ABLIM2-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABLIM2→partner) and Y-score (partner→ABLIM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCTDGF1P1 →+0.090+5.355<.001.00533
UCECPSMC3IP →+0.627+1.733<.001<.00133
UCECRN7SL248P →+0.035+2.437<.001.00533
UCECH2AZ1 →+0.455+1.401.001.00233
UCECSFXN1 →+0.489+2.129<.001<.00133
UCECCORO1C →+0.486+1.787<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,819 associations by consensus.

TDGF1P1 by ABLIM2 expression — LIHC

Box plot of TDGF1P1 in ABLIM2-low vs ABLIM2-high samples in LIHC.

Explore this box plot interactively →

Exploration