ABI2

Across TCGA patient cohorts, ABI2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,862 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ABI2-associated genes across cancer lineages are KLF12, OLFM1, and TRPC1. Each is linked with ABI2 in more than 6 cancer types. Because this analysis shows association rather than direction, both ABI2-to-partner and partner-to-ABI2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABI2 versus KLF12 in HNSC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABI2→partner) and Y-score (partner→ABI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	KLF12 →	+0.993	+0.422	<.001	<.001	3	7
HNSC	OLFM1 →	+1.101	+0.245	<.001	.005	3	7
UCEC	TRPC1 →	+0.868	+0.301	<.001	<.001	3	7
HNSC	PRKD1 →	+1.148	+0.396	<.001	<.001	3	7
HNSC	FAM66C →	+0.987	+0.407	<.001	<.001	3	7
BRCA	CYBRD1 →	+1.283	+0.209	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,862 associations by consensus.

ABI2 vs KLF12 — HNSC

Explore this scatter interactively →