ABI2

Across TCGA cell cohorts, ABI2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,571 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ABI2-associated GO terms across cancer lineages are Protein monoubiquitination, Centrosome cycle, and Positive regulation of organelle assembly. Each is linked with ABI2 in more than 15 cancer types. Because this analysis shows association rather than direction, both ABI2-to-partner and partner-to-ABI2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein monoubiquitination grouped by ABI2-low versus ABI2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABI2→partner) and Y-score (partner→ABI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein monoubiquitination →	+0.096	+1.113	.001	.003	3	16
UPPER_AERODIGESTIVE_TRACT	Centrosome cycle →	+0.097	+0.958	<.001	.006	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of organelle assembly →	+0.085	+1.600	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cilium assembly →	+0.103	+1.028	<.001	.003	3	15
STOMACH	Negative regulation of gene expression, epigenetic →	+0.069	+1.156	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Microtubule cytoskeleton organization involved in mitosis →	+0.095	+1.062	.009	.007	2	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,571 associations by consensus.

Protein monoubiquitination by ABI2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →