ABI1

Across TCGA patient cohorts, ABI1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,267 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ABI1-associated genes across cancer lineages are CCNY, YME1L1, and GLUD1. Each is linked with ABI1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ABI1-to-partner and partner-to-ABI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABI1 versus CCNY in LSCC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABI1→partner) and Y-score (partner→ABI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CCNY →	+0.472	+0.179	<.001	<.001	3	5
LSCC	YME1L1 →	+0.385	+0.157	<.001	<.001	3	5
UCEC	GLUD1 →	+0.523	+0.269	<.001	<.001	3	5
HNSC	CRYBG2 →	+0.913	+0.184	.002	<.001	3	5
GBM	ARHGAP21 →	+0.527	+0.283	<.001	.006	2	5
UCEC	ACBD5 →	+0.486	+0.303	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,267 associations by consensus.

ABI1 vs CCNY — LSCC

Explore this scatter interactively →