ABI1

Across TCGA pan-cancer cohorts, ABI1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of ABI1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where ABI1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ABI1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

LIHC, KICH, and LUSC are the cancer types where ABI1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ABI1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Female	II,III,IV	+0.976	<.001	9	view →
KICH	Female	All	−1.427	<.001	8	view →
LUSC	All	All	+0.538	<.001	5	view →
BLCA	Male	III,IV	+0.694	.026	4	view →
HNSC	All	All	+0.339	.018	4	view →
BRCA	All	All	+0.161	.009	4	view →
CHOL	Male	All	+2.291	<.001	3	view →
STAD	All	All	+0.389	.017	2	view →
READ	All	III,IV	+0.329	.018	2	view →
COAD	Male	All	+0.238	.021	2	view →
KIRC	All	All	+0.194	.008	2	view →
THCA	All	All	−0.186	.026	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

ABI1–LIHC

Open the LIHC breakdown →