ABI1

Across TCGA cell cohorts, ABI1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,821 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ABI1-associated GO terms across cancer lineages are Negative regulation of protein depolymerization, Regulation of Golgi organization, and Regulation of establishment of cell polarity. Each is linked with ABI1 in more than 10 cancer types. Because this analysis shows association rather than direction, both ABI1-to-partner and partner-to-ABI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein depolymerization grouped by ABI1-low versus ABI1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABI1→partner) and Y-score (partner→ABI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of protein depolymerization →	+0.096	+0.557	<.001	<.001	3	11
LUNG_SCLC	Regulation of Golgi organization →	+0.055	+0.557	.004	.007	3	10
STOMACH	Regulation of establishment of cell polarity →	+0.171	+0.599	<.001	.004	3	10
KIDNEY	Negative regulation of protein-containing complex disassembly →	+0.098	+0.711	.001	.001	3	10
STOMACH	Regulation of intracellular steroid hormone receptor signaling pathway →	+0.095	+0.619	<.001	.005	3	9
BREAST	Phosphatidylinositol biosynthetic process →	+0.054	+0.876	.001	.002	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,821 associations by consensus.

Negative regulation of protein depolymerization by ABI1 expression — SOFT_TISSUE

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