ABI1

Across TCGA cell cohorts, ABI1 mutation is significantly associated with the RNA expression of many other genes, with 43 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ABI1-associated genes across cancer lineages are C16orf90, ITIH6, and CPN1. Each is linked with ABI1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABI1-to-partner and partner-to-ABI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C16orf90 grouped by ABI1-low versus ABI1-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABI1→partner) and Y-score (partner→ABI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	C16orf90 →	+0.023	+5.087	<.001	.004	3	1
BLOOD_Leukemia	ITIH6 →	+0.019	+3.754	<.001	.006	3	1
BLOOD_Leukemia	CPN1 →	+0.103	+3.820	.001	.004	3	1
BLOOD_Leukemia	CRHR1 →	+0.181	+3.995	.005	.002	3	1
BLOOD_Leukemia	BRDT →	+0.149	+4.664	<.001	<.001	3	1
BLOOD_Leukemia	ASZ1 →	+0.086	+3.567	.005	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

C16orf90 by ABI1 expression — URINARY_TRACT

Explore this box plot interactively →