ABHD8

Across TCGA cell cohorts, ABHD8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,719 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABHD8-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Endosomal transport, and Regulation of anaphase-promoting complex-dependent catabolic process. Each is linked with ABHD8 in more than 13 cancer types. Because this analysis shows association rather than direction, both ABHD8-to-partner and partner-to-ABHD8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by ABHD8-low versus ABHD8-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD8→partner) and Y-score (partner→ABHD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of myoblast fusion →	+0.125	+1.912	<.001	<.001	3	14
LARGE_INTESTINE	Endosomal transport →	+0.048	+1.258	<.001	<.001	3	13
BONE	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.147	+1.267	<.001	<.001	3	13
BONE	Negative regulation of DNA-templated transcription initiation →	+0.113	+1.138	<.001	<.001	3	13
STOMACH	Protein polyubiquitination →	+0.056	+1.520	<.001	.003	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium movement →	-0.103	-1.256	.001	.005	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,719 associations by consensus.

Negative regulation of myoblast fusion by ABHD8 expression — STOMACH

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