ABHD6

Across TCGA patient cohorts, ABHD6 protein abundance is significantly associated with the RNA expression of many other genes, with 8,645 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ABHD6-associated genes across cancer lineages are SMIM2-IT1, H3C7, and ASAH1. Each is linked with ABHD6 in more than 2 cancer types. Because this analysis shows association rather than direction, both ABHD6-to-partner and partner-to-ABHD6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABHD6 versus SMIM2-IT1 in CCRCC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD6→partner) and Y-score (partner→ABHD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SMIM2-IT1 →	+1.238	+0.321	<.001	<.001	3	3
UCEC	H3C7 →	-2.015	-0.347	<.001	.007	3	3
GBM	ASAH1 →	+0.504	+0.353	<.001	.001	3	3
LSCC	ISYNA1 →	-0.901	-0.299	<.001	<.001	3	3
LUAD	SIX1 →	-1.125	-0.197	.003	.003	3	3
LSCC	RBM38 →	-0.849	-0.276	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,645 associations by consensus.

ABHD6 vs SMIM2-IT1 — CCRCC

Explore this scatter interactively →