ABHD17C

Across TCGA cell cohorts, ABHD17C mutation is significantly associated with the mutation status of many other genes, with 978 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABHD17C-associated genes across cancer lineages are DGKE, MED13, and RREB1. Each is linked with ABHD17C in more than 2 cancer types. Because this analysis shows association rather than direction, both ABHD17C-to-partner and partner-to-ABHD17C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DGKE grouped by ABHD17C-low versus ABHD17C-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD17C→partner) and Y-score (partner→ABHD17C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	DGKE →	+6.044	+6.044	.001	.001	1	3
CNS	MED13 →	+6.044	+6.044	.001	.001	1	3
CNS	RREB1 →	+4.459	+5.277	.005	.005	1	3
CNS	NCBP3 →	+5.044	+5.614	.003	.003	1	3
SKIN	ASNSD1 →	+4.239	+5.053	.007	.007	1	2
SKIN	HERC3 →	+4.824	+5.392	.004	.004	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 978 associations by consensus.

DGKE by ABHD17C expression — CNS

Explore this box plot interactively →