ABHD17A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ABHD17A mutation is significantly associated with the RNA expression of many other genes, with 1,189 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABHD17A-associated genes across cancer lineages are FAM96AP1, LINC00351, and BTBD10. Each is linked with ABHD17A in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD17A-to-partner and partner-to-ABHD17A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM96AP1 grouped by ABHD17A-low versus ABHD17A-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD17A→partner) and Y-score (partner→ABHD17A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMFAM96AP1 →+0.079+5.797<.001.00132
CESCLINC00351 →+0.162+5.201<.001.00732
UCECBTBD10 →+0.457+2.130.003.00331
UCECLIN7C →+0.529+3.628.004.00131
UCECAPIP →+0.440+3.467.008.00231
UCECGLB1L2 →-0.710-2.684.006.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,189 associations by consensus.

FAM96AP1 by ABHD17A expression — SKCM

Box plot of FAM96AP1 in ABHD17A-low vs ABHD17A-high samples in SKCM.

Explore this box plot interactively →

Exploration