ABHD17A

Across TCGA patient cohorts, ABHD17A mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABHD17A-associated genes across cancer lineages are eEF2, eIF4E, and FOXO3a_pS318_S321. Each is linked with ABHD17A in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD17A-to-partner and partner-to-ABHD17A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by ABHD17A-low versus ABHD17A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD17A→partner) and Y-score (partner→ABHD17A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.339	+2.000	.035	.032	3	1
UCEC	eIF4E →	+0.244	+3.335	.010	.005	3	1
UCEC	FOXO3a_pS318_S321 →	-0.122	-2.000	.030	.032	3	1
UCEC	Ku80 →	+0.265	+3.469	.012	.002	3	1
UCEC	MEK1 →	+0.328	+3.169	.047	.019	3	1
UCEC	NF2 →	+0.290	+3.321	.002	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

eEF2 by ABHD17A expression — UCEC

Explore this box plot interactively →