ABHD17A

Across TCGA cell cohorts, ABHD17A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,431 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ABHD17A-associated GO terms across cancer lineages are Positive regulation of anaphase-promoting complex-dependent catabolic process, Energy coupled proton transmembrane transport, against electrochemical gradient, and Electron transport coupled proton transport. Each is linked with ABHD17A in more than 18 cancer types. Because this analysis shows association rather than direction, both ABHD17A-to-partner and partner-to-ABHD17A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of anaphase-promoting complex-dependent catabolic process grouped by ABHD17A-low versus ABHD17A-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD17A→partner) and Y-score (partner→ABHD17A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.144	+0.876	<.001	<.001	3	19
BONE	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.098	+1.472	.007	.001	3	17
BONE	Electron transport coupled proton transport →	+0.098	+1.472	.007	.001	3	17
BONE	Cytoplasm protein quality control by the ubiquitin-proteasome system →	+0.166	+1.015	<.001	<.001	3	15
BONE	Cytoplasm protein quality control →	+0.145	+1.014	<.001	<.001	3	15
BONE	Positive regulation of protein localization to chromatin →	+0.104	+1.046	.004	.006	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,431 associations by consensus.

Positive regulation of anaphase-promoting complex-dependent catabolic process by ABHD17A expression — PANCREAS

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