ABHD17A

Across TCGA cell cohorts, ABHD17A mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ABHD17A-associated genes across cancer lineages are PHOX2B, IRX4, and CRHR1. Each is linked with ABHD17A in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD17A-to-partner and partner-to-ABHD17A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PHOX2B grouped by ABHD17A-low versus ABHD17A-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD17A→partner) and Y-score (partner→ABHD17A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PHOX2B →	+0.018	+3.687	<.001	<.001	3	1
BLOOD_Leukemia	IRX4 →	+0.119	+2.884	<.001	.009	3	1
BLOOD_Leukemia	CRHR1 →	+0.213	+3.258	<.001	.001	3	1
BLOOD_Leukemia	CFAP300 →	+0.047	+3.568	.008	.003	3	1
BLOOD_Leukemia	BRDT →	+0.105	+3.664	<.001	.001	3	1
BLOOD_Leukemia	BTBD16 →	+0.070	+4.181	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

PHOX2B by ABHD17A expression — BLOOD_Leukemia

Explore this box plot interactively →